OFFSPRING PRODUCTION OF OVARIAN ORGANOIDS DERIVED FROM SPERMATOGONIAL STEM CELLS BY DEFINED FACTORS WITH CHROMATIN REORGANIZATION

Offspring production of ovarian organoids derived from spermatogonial stem cells by defined factors with chromatin reorganization

Introduction: Fate determination of germline stem cells remains poorly understood at the chromatin structure level.Objectives: Our research hopes to develop successful offspring production of ovarian organoids derived from spermatogonial stem cells (SSCs) by defined factors.Methods: The offspring production from oocytes transdifferentiated from mou

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Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.

BackgroundObservational studies have reported that higher plasma 25-hydroxyvitamin D (25[OH]D) concentrations are associated with lower risks of diabetes, but Brow Brush it is unclear if these associations are causal.The aim of this study was to test the relevance of 25(OH)D for type 2 diabetes using genetically instrumented differences in plasma 2

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